He was one of the original cast members of "E.R.": The amazingly talented George Clooney played the role of the pediatrician "Doctor Doug Ross" and was, naturally, always very popular with the female viewer. He stuck with the show until 1999, although he'd already had success as a film actor, starting in 1996 with "From Dusk Till Dawn". He made two more appearances on "E.R", once in 2000 and another one in 2009.